Makhdoom (Arabic: مخدوم, meaning one who is served and sometimes spelled Makhdum,Bengali: মখদুম, romanized: Mokhdumis) is an Arabic word meaning "Teacher of Sunnah." It is a title and group of Pirs, and landlords in South and Central Asia.

• Makhdoom Yahya Maneri (1263 - 1379 AD) – a mystic who lived in Bihar Sharif
• Makhdoom Jahaniyan Jahangasht (1308- 1384 AD) - a world-traveling Sufi Saint who was spiritual master of king Firoz Shah Tughlaq, Ashraf Jahangir Simnani and 80 makhdooms of his time.
• Hamza Makhdoom – a mystic from Kashmir (d. 1563 AD)
• Zainuddin Makhdoom II - A mystic from Malabar
• Makhdoom Mian Mir – a Sufi mystic from Lahore who laid first foundation of the Golden Temple in Amritsar
• Makhdoom Ali Mahimi – a Sufi saint from the Konkan in India
• \Makhdoom Syed Yousaf Raza Gillani – a former Prime Minister of Pakistan
• Makhdoom Muhammad Ameen Faheem – a former Pakistani politician and leader of PPP
• Makhdoom Syed Faisal Saleh Hayat – a Pakistani politician affiliated with PML-Q and former Interior Minister of Pakistan
• Makhdoom Muhammad Javed Hashmi – a Pakistani politician, and central leader of PML-N
• Makhdoom Ali Khan – a former Attorney General of Pakistan
• Makhdoom Khusro Bakhtiar – a Pakistani politician, former Minister for Industries & Production of Pakistan
• Makhdoom Mohiuddin – an Urdu poet and Marxist politician from India
• Sayed Makhdoom Raheen – an ambassador of Afghanistan to India and former Information Minister of Afghanistan
• Makhdoom Shah Mehmood Qureshi – a Pakistani politician, former Foreign Minister of Pakistan
• Makhdoom Muhammad Zaman Talib-ul-Mola – the founding member of Pakistan Peoples Party and famous Sindhi poet
• Makhdoom Shahabuddin – a Pakistani politician
• Ammar Aziz - a Pakistani filmmaker
• Shah Makhdum Abdul Quddus Rupos - a Sufi saint from Shahzadpur in Bangladesh.
• Syed Muhammad Idrees Makhdoom - a Anty Sufi saint from the Jacobabad in Pakistan.
• Makhdoom Abdul Rauf Qureshi - District education officer and Sajadah Nasheen Dargah Baal MubarakRohri in Pakistan.
• Makhdoom Muhammad Usman Qureshi - Al Zuhravi Banu Zuhrah - Al Yemani- Al Sindhi - Al Darbelvi Darbelo ]] -

A Sufi Saint, Theologian, Poet, renowned Islamic scholar and jurist from Sindh, whose contributions to knowledge and spirituality left an indelible mark on history. his life was dedicated to the propagation of Islamic teachings, the guidance of the community, and the pursuit of spiritual excellence. He died in 1593 AD (1002 AH) at the age of 102 and was interred in Darbelo's Qureshi (Makhdoom) Mohalla, south of Jamia Mosque in Darbelo Pakistan

• Allama Mufti Makhdoom Abdul Aleem Qureshi - Al Zuhravi Banu Zuhrah- Al Sindhi - Al Darbelvi Darbelo ]] - A Descendant of Makhdoom Muhammad Usman Qureshi , Makhdoom Abdul Aleem was a Religious Scholar, A Islamic Theologian and The Imam of Grand Mosque ( Jamia Masjid ) Darbello