Manderscheid can refer to:

• Manderscheid, Bernkastel-Wittlich, a town in Germany
• Manderscheid (Verbandsgemeinde), a former collective municipality in Bernkastel-Wittlich, Rhineland-Palatinate, Germany
• Manderscheid, Bitburg-Prüm a village in Germany
• County of Manderscheid, historical state of the Holy Roman Empire centered on Manderscheid, Bernkastel-Wittlich