Pedro Rodriguez may refer to:

• Pedro Rodríguez (athlete), Cuban shot putter who won in the Athletics at the 1926 Central American and Caribbean Games
• Pedro Rodríguez (racing driver) (1940–1971), Mexican racing driver
• Pedro Rodríguez (cyclist, born 1950), Cuban cyclist
• Pedro Rodríguez (water polo), Cuban water polo player
• Pedro Rodríguez (cyclist, born 1966), Ecuadorian cyclist
• Pedro Rodríguez (weightlifter), Cuban weightlifter who won in the Weightlifting at the 1991 Pan American Games
• Pedro (footballer, born 1987) (Pedro Eliezer Rodríguez Ledesma), Spanish footballer, played for Barcelona and Chelsea
• Pedro Rodríguez (motorcyclist) (born 1994), Spanish Grand Prix motorcycle racer
• Pedro Rodríguez (cyclist, born 1994), Ecuadorian cyclist at the 2013 UCI Road World Championship
• Pedro Rodríguez Álvarez (born 1990), Spanish-Hungarian handball player

• Pedro Rodríguez (cardinal) (died 1310), bishop of Burgos
• Pedro Rodriguez de Miranda (1696–1766), Spanish painter of the late-Baroque period
• Pedro Rodríguez, Count of Campomanes (1723–1802), Spanish statesman and writer
• Pedro Rodríguez (politician) (1869–1932), Philippine politician
• Pedro Jesús Rodríguez (1907–1982), Chilean lawyer, academic and politician
• Pedro Rodríguez (soldier) (1912–1999), Puerto Rican Korean War hero who won two Silver Star Medals
• Pedro Rodriguez (scientist) (born 1953), Puerto Rican scientist and inventor in NASA
• Pedro A. Rodríguez (born 1968), PPD member of the 15th Legislative Assembly of Puerto Rico
• Pedro Rodriguez (theologian) (fl. 1980s–1990s), Spanish theologian
• Pedro Rodríguez (Paraguayan politician), president of the Chamber of Deputies of Paraguay 2017–2018

• Pedro-Rodríguez, a municipality in the province of Ávila, Castile and León, Spain
• Pedro Rodrigues Filho, a prolific serial killer