SAC or Sac may refer to:

• Santa Ana College, California, US
• San Antonio College, Texas, US
• St. Andrew's College, Aurora, Canada
• Students' Administrative Council, University of Toronto, Canada
• SISD Student Activities Complex, in El Paso, Texas, US
• School-assessed coursework for Victorian Certificate of Education
• Student Activity Complex, in Laredo, Texas, US

• NATO Strategic Airlift Capability, multinational transport aircraft initiative
• Senior Aircraftman, a Royal Air Force rank
• Senior Assistant Commissioner, a rank in the police of Singapore and Malaysia
• Southern Air Command (India), of the Indian Air Force
• Special Agent in Charge of a criminal investigation
• State Administration Council, governing Myanmar after the 2021 coup d'état
• Special advisory committee, of the Canadian government

• Second Artillery Corps, later the People's Liberation Army Rocket Force, China
• Shenyang Aircraft Corporation, Chinese aircraft manufacturer
• Standardization Administration of China
• Securities Association of China

• Special Activities Center of the CIA
• California State Prison, Sacramento
• Strategic Air Command, active 1946-1992, now an inactive USAF major command (MAJCOM)
• President's Science Advisory Committee

• Sacramento Kings, a National Basketball Association team that uses this abbreviation for box scores and television scoring displays
• Sooner Athletic Conference
• South Atlantic Conference
• Swiss Alpine Club

• Central Organisation of the Workers of Sweden (in Swedish: Sveriges Arbetares Centralorganisation, SAC - Syndikalisterna)
• S.A.C. Capital Advisors, a hedge fund managed by Steven A. Cohen
• Satélite Argentino Científico, Argentine research satellites of Comisión Nacional de Actividades Espaciales
• Scottish Arbitration Centre
• Seoul Arts Center, South Korea
• Service d'Action Civique, a Gaullist organisation
• Shakespeare Authorship Coalition,'S A C', Claremont, California
• Singapore Accountancy Commission
• Societas Apostolatus Catholici, a Catholic religious congregation
• Society of the Catholic Apostolate, or Pallotines, a religious order
• Soldiers of Aryan Culture, an American white supremacist prison gang
• Songwriters Association of Canada
• Space Applications Centre, India
• State Affairs Commission of North Korea
• Sveriges Arbetares Centralorganisation, a trade union federation in Sweden
• Superior Art Creations, a computer art scene group
• The Society of Arts and Crafts of Boston, US, since 1897

• S-Allyl cysteine, a chemical constituent of garlic
• Sac spider, a taxon
• Source of activation confusion model, in psychology
• Spindle assembly checkpoint, in biology
• Tin-silver-copper (SnAgCu), a solder formulation
• Supplemental access control, electronic travel document security features
• Soluble adenylyl cyclase

• SA-C programming language
• S.A.C. (control code), in the 1950s FIELDATA
• SAC programming language
• Special Administration Console of Windows Emergency Management Services
• Strict Avalanche Criterion in cryptography
• Selected Areas in Cryptography, an annual cryptography conference
• Symposium on Applied Computing, an annual conference
• Spatial Audio Coding or MPEG Surround

• SAC (gene)
• Amniotic sac
• Anal sac or anal gland
• Bursa sac or bursa
• Chorion
• Dural sac, a structure of spinal cord
• Egg sac, the reproductive structure of a spider
• Fecal sac
• Gestational sac
• Greater sac
• Gular skin or throat sac
• Ink sac
• Lacrimal sac, eye-and-nose-associated structure
• Lesser sac
• Ovule or embryo sac
• Pleural cavity or pleural sac
• Synovial sac, joint component
• Venom sac, in venom-secreting animals
• Vestibular sacs (disambiguation)
• Viscid sac
• Vocal sac
• Yolk sac

• Sacramento Executive Airport (IATA code)
• Sacramento Valley Rail Station (Amtrak station code)
• St Albans City railway station (National Rail station code)
• Sports activity coupe, a BMW class of cars
• Self-adjusting clutch in the BMW 5 Series

• Sac City, Iowa
• Sac County, Iowa
• Sac River, Missouri
• Nickname of Sacramento, California

• St Anne's Cathedral, Belfast
• St Anne's Cathedral, Debrecen

• Sač, a baking vessel in the Balkans and the Middle East
• Ghost in the Shell: Stand Alone Complex (and GITS: SAC 2nd GIG), a Japanese TV series
• Sac language (ISO 639:sac)
• Sac (people), a North American tribe
• Sacrifice bunt, in baseball
• Slow air chamber, of a Native American flute
• Special Area of Conservation, in the EU and UK
• Summit Athletic Conference (IHSAA), Fort Wayne, Indiana, US
• SAC-46 (handgun), pistol, USA, 1945

• Sack (disambiguation)
• All pages with titles containing sac